Monday, April 16, 2012

Metformin Trial

About 7 years ago, Eric and I sought help from a reproductive endocrinologist because we were having trouble conceiving. I was diagnosed with Polycystic Ovarian Syndrome.

Along with a whole gamut of drugs to help me ovulate, I was also given a drug called Metformin. Metformin is typically taken by diabetics, but was prescribed for me to reduce insulin levels and promote normal ovarian function.

It worked. I was on it for a few years but eventually went off it when we moved to Minnesota. I honestly have no idea why I went off it. It was probably because I wasn't in the market for more kids.

Fast forward to last week. I was googling more breast cancer trials. I am intrigued by new drugs that may be the answer to my prayers. I came across a Metformin trial that immediately peaked my interest.

I asked Dr. Hartung about it today and was told that I actually qualified for the trial. There's a HUGE study going on right now that approximately 3580 people will participate in. Half of the patients will receive Metformin, the other half will receive a placebo. The study should take about 3 years to fill enrollment and the results should be known in about 6 years. I did the paperwork and was signed up to begin next week.

I thought about it all the way home from Woodbury, when it suddenly occurred to me, why do I want to risk taking a placebo for 3-6 years when a drug that I KNOW my body tolerates and only costs pennies per day is available to me?

I immediately called my primary family doctor and told her about the study. I asked if I could go back on Metformin to treat my PCOS.

I'm excited to report that my prescription is at Target right now waiting for me to pick it up.
I will start taking the Met with my Tamoxifen tomorrow.

I will also be officially dropping out of the trial tomorrow. I can't take the chance that I would get a placebo.

I have a good feeling about this. :)

1 comment:

  1. That is really interesting! I've never heard of it being used for anything other than diabetes,